Chris Arthur's approach aims at a systematic re-ordering of Marx's categories. This article argues that his approach is actually a different ordering of different categories that are positioned within a specific theoretical whole, a Hegelian re-interpretation of Marx and especially of abstract labour, which distances itself from Marx. While the debate has focused mainly on the philosophical aspects of Arthur's work, its economic features have not been the object of a systematic analysis. Yet, a full assessment of the 'New Dialectics' (...) should include explicitly a systematic internal critique of its economic dimensions. The aim of this article is to assess the internal consistency of the economic ramifications of the 'New Dialectics'. The focus is on the notions of abstract labour, concrete labour, and exploitation. Arthur's faithfulness to Marx, or correspondence to Marx's quotations, is not the criterion used to assess the 'New Dialectics'. Rather, the criterion is whether it discovers logical inconsistencies in Capital and is itself free from inconsistencies. The answer is negative in both cases. (shrink)

The fulcrum of this work is knowledge: what it is and how it is generated within the context of a capitalist society. First, Marx’s analysis of the objective labour process is extended to the mental labour process. Then, objective and mental labour processes are defined in terms of objective and mental transformations, with consideration paid to which of the two types of transformation is determinant. This requires a discussion of dialectical logic and formal logic. Within dialectical logic, two types of (...) processes are introduced: open ended and pre-determined. It is argued that computers (both traditional and quantum) and Artificial Intelligence cannot generate new knowledge, because they (a) rely on formal logic, i.e. they cannot engage in open-ended dialectical processes, and (b) are impervious to social determination. Connectedly, Artificial Intelligence systems such as ChatGPT cannot be a substitute for human thought or writing, because of the inevitability of ‘model collapse’. Next, focus is shifted to a specific form of knowledge: the ‘Copenhagen interpretation’ of quantum mechanics. It is shown that this interpretation is steeped in irrationalism and that it is a variant of pro-capitalist ideology. Finally, the social-historical roots of this ideology are revealed. (shrink)

Brenner's ‘The Economics of Global Turbulence’ is a review of the world economy in the second half of the 20th century and its momentous changes. It deals with a wide range of issues and developments and is supported by a wealth of statistical and historical material. At the same time, it debunks many of the myths upon which recent history has been written. Perhaps even more importantly, it seeks the causes of crises in the laws of motion of capital itself.

This work focuses exclusively on the modern economic aspects of imperialism. We define it as a persistent and long-term net appropriation of surplus value by the high-technology imperialist countries from the low-technology dominated countries. This process is placed within the secular tendential fall in profitability, not only in the imperialist countries but also in the dominated ones. We identify four channels through which surplus value flows to the imperialist countries: currency seigniorage; income flows from capital investments; unequal exchange through trade; (...) and changes in exchange rates. We pay particular attention to the theorisation and quantification of international UE and of exchange-rate movements. Concerning UE, we extend Marx’s transformation procedure to the international setting. We use two variables in the analysis of UE: the organic composition of capital and the rate of exploitation, and we measure which of these two variables is more important in contributing to UE transfers. We research a time span longer than in any previous study. We also introduce the distinction between narrow and broad unequal exchange according to whether two countries are assumed to trade only with each other or also with the rest of the world. As for the analysis of the exchange rates as a channel for appropriation of international surplus value, we reject conventional approaches because they are rooted in equilibrium theory. We find very strong empirical evidence that exchange rates tend towards the point at which the productivities are equalised. This is only a tendency because this equalisation is inherently incompatible with the nature of imperialism. Finally, given its topicality, we apply our analysis to the relation between the US and China and find that China is not an imperialist country according to our definition and data. (shrink)

For a general formulation of the undecidability and incompleteness theorems one has to characterize precisely the notion of formal system. Such a characterization is provided by the proposal to identify the intuitive concept of effectively calculable function with that of partial recursive function. A proper understanding of this identification, which is known under the name of "Church's thesis", is crucial for a philosophical assessment of these metamathematical results. The undecidability and incompleteness theorems suggest one major but certainly not the (...) only reason for interest in Church's thesis. The thesis provides a sharp characterization of a concept that has played an epistemologically motivated role in many logical and foundational investigations and that has been appealed to in methodological discussions concerning computational approaches in cognitive psychology. ;In spite of these various motives of interest a detailed philosophical analysis of the meaning and the epistemological status of Church's thesis has been neglected; a thorough and balanced presentation of arguments for it is lacking. This seems to me to be due to two widespread views of the thesis, both tending to discourage analytical work. According to the first of these views, Church's thesis is unproblematic because the classical arguments for the identification are convincing. According to the second view, it is hopeless to try to evaluate the adequacy of a proposed mathematical characterization of effectiveness, because the intuitive notion is too vague. The analysis undertaken in this thesis conflicts with both views. ;I All classical arguments for Church's thesis, including Turing's, have unconvincing aspects. ;II Some generalizations of Turing's work show that unconvincing aspects of Turing's argument can be dispensed with and provide conceptually significant contributions to the problem of a "natural" mathematical characterization of the mechanically calculable functions. ;III One can isolate meanings of effectiveness conceptually more inclusive than mechanical calculability and distinguish between corresponding interpretations of Church's thesis. ;The analytical work supporting these claims bears significantly on the philosophical issues mentioned above: it plays a crucial role in a philosophical evaluation of the undecidability and incompleteness theorems and in a clarification of the conceptual background of computational approaches in cognitive psychology. (shrink)

Truth is a key notion in Ockham’s philosophical reductionist program, a notion that has been the object of contrasting interpretations in scholarship. My interpretation is that, for Ockham, ‘being true’ expresses an epistemological relation, namely the one through which our mind reflects on a proposition of language, compares it with an extra-mental state of affairs, and thus ascertains their correspondence. Placing truth at a point of intersection of language with mind and reality, Ockham’s interpretation of Aristotle’s characterization of philosophy as (...) the science of truth comes to be innovative. For Ockham, philosophy is a meticulous training of interpretation of language in order to account correctly for the truth-value of propositions. (shrink)

Extant models of moral judgment assume that an action’s intentionality precedes assignments of blame. Knobe (2003b) challenged this fundamental order and proposed instead that the badness or blameworthiness of an action directs (and thus unduly biases) people’s intentionality judgments. His and other researchers’ studies suggested that blameworthy actions are considered intentional even when the agent lacks skill (e.g., killing somebody with a lucky shot) whereas equivalent neutral actions are not (e.g., luckily hitting a bull’s-eye). The present five studies offer an (...) alternative account of these provocative findings. We suggest that people see the morally significant action examined in previous studies (killing) as accomplished by a basic action (pressing the trigger) for which an unskilled agent still has sufficient skill. Studies 1 through 3 show that when this basic action is performed unskillfully or is absent, people are far less likely to view the killing as intentional, demonstrating that intentionality judgments, even about immoral actions, are guided by skill information. Studies 4 and 5 further show that a neutral action such as hitting the bull’s-eye is more difficult than killing and that difficult actions are less often judged intentional. When difficulty is held constant, people’s intentionality judgments are fully responsive to skill information regardless of moral valence. The present studies thus speak against the hypothesis of a moral evaluation bias in intentionality judgments and instead document people’s sensitivity to subtle features of human action. (shrink)

In this paper, we report on the development of The Sustainable Port video game, which aims to simulate the complex dynamics and decisions occurring in the present and future development of a port area considering environmental aspects (CO2 emissions) and profit. To evaluate if this game fulfills its purpose, we asked 75 students and 34 employees at the Port of Rotterdam (PoR) to play The Sustainable Port. Our results show that PoR employees score higher than students suggesting a transfer between (...) real-life experience of being an employee in the port and performance in the game. Furthermore, port participants reported that The Sustainable Port can be successfully used to start discussions about the future of the Port of Rotterdam and to raise awareness about the complexity characterizing the decision-making processes occurring in a port environment. Our results, taken together, provide evidence of the effectiveness of The Sustainable Port in simulating dynamics occurring in port development and give us optimism about future applications. (shrink)

Artificial agents are progressively becoming more present in everyday-life situations and more sophisticated in their interaction affordances. In some specific cases, like Google Duplex, GPT-3 bots or Deep Mind’s AlphaGo Zero, their capabilities reach or exceed human levels. The use contexts of everyday life necessitate making such agents understandable by laypeople. At the same time, displaying human levels of social behavior has kindled the debate over the adoption of Dennett’s ‘intentional stance’. By means of a comparative analysis of the literature (...) on robots and virtual agents, we defend the thesis that approaching these artificial agents ‘as if’ they had intentions and forms of social, goal-oriented rationality is the only way to deal with their complexity on a daily base. Specifically, we claim that this is the only viable strategy for non-expert users to understand, predict and perhaps learn from artificial agents’ behavior in everyday social contexts. Furthermore, we argue that as long as agents are transparent about their design principles and functionality, attributing intentions to their actions is not only essential, but also ethical. Additionally, we propose design guidelines inspired by the debate over the adoption of the intentional stance. (shrink)

This article examines ethical implications of the growing AI carbon footprint, focusing on the fair distribution of prospective responsibilities among groups of involved actors. First, major groups of involved actors are identified, including AI scientists, AI industry, and AI infrastructure providers, from datacenters to electrical energy suppliers. Second, responsibilities of AI scientists concerning climate warming mitigation actions are disentangled from responsibilities of other involved actors. Third, to implement these responsibilities nudging interventions are suggested, leveraging on AI competitive games which would (...) prize research combining better system accuracy with greater computational and energy efficiency. Finally, in addition to the AI carbon footprint, it is argued that another ethical issue with a genuinely global dimension is now emerging in the AI ethics agenda. This issue concerns the threats that AI-powered cyberweapons pose to the digital command, control, and communication infrastructure of nuclear weapons systems. (shrink)

This study aimed to identify real-life experts working for a port authority and lay people (students) who played The Sustainable Port, a serious game aiming to simulate the dynamics occurring in a port area. To achieve this goal, we analyzed eye gaze data collected noninvasively using low-grade webcams from 28 participants working for the port authority of the Port of Rotterdam and 66 students. Such data were used for a classification task implemented using a MiniRocket classifier, an algorithm used for (...) time-series classification. The classifier reached an F1 score of 0.75 (SD = 0.07), a PR AUC of 0.73 (SD = 0.14), and an ROC AUC of 0.75 (SD = 0.15) providing evidence that it is possible to identify real-life experts about maritime port management using data that can be obtained from a webcam. We speculate that the gaze direction used to train the MiniRocket may contain relevant information about the cognitive processes and decisions occurring throughout the gameplay. We suggest that the methods here presented not only can be used to detect experts playing simulations, such as serious games, but also to identify experts tackling screen-presented tasks. (shrink)

Moral judgments about an agent's behavior are enmeshed with inferences about the agent's mind. Folk psychology—the system that enables such inferences—therefore lies at the heart of moral judgment. We examine three related folk-psychological concepts that together shape people's judgments of blame: intentionality, choice, and free will. We discuss people's understanding and use of these concepts, address recent findings that challenge the autonomous role of these concepts in moral judgment, and conclude that choice is the fundamental concept of the three, defining (...) the core of folk psychology in moral judgment. (shrink)

The logic of gift and gratuitousness in business activity raised by the encyclical Caritas in Veritate stresses a deeper critical evaluation of the category of relation. The logic of gift in business includes two aspects. The first is considering the logic of gift as a new conceptual lens in order to view business relationship beyond contractual logic. In this view, it is crucial to see the circulation of goods as instrumental for the development of relationships. The second aspect is to (...) qualify the relationships established through the gift, and to think about the motivation in gift-giving, which has an ethical content. We give because we have received, and through gift-giving we develop relationships that have a high ‘bonding value’. Analysing the logic of gift in business management may permit us to gain an understanding of the ambiguity of gift-giving in organizations. Looking at the relationships between organizations and employees, and organizations and customers, we can discover why the logic of gift is often misunderstood or abused in its application, and how it should be applied to be more consistent with the message of Caritas in Veritate. (shrink)

Although the analogy between macroscopic machines and biological molecular devices plays an important role in the conceptual framework of both neo-mechanistic accounts and nanotechnology, it has recently been claimed that certain complex molecular devices cannot be considered machines since they are subject to physicochemical forces that are different from those of macroscopic machines. However, the structural and physicochemical conditions that allow both macroscopic machines and microscopic devices to work and perform new functions, through a combination of elemental functional parts, have (...) not yet been examined. In order to fill this void, this paper has a threefold aim: first, to clarify the structural and organisational conditions of macroscopic machines and microscopic devices; second, to determine whether the machine-like analogy fits nanoscale devices; and third, to assess whether the machine-like analogy is appropriate for describing the behaviour of some biological macromolecules. Finally, the paper gives an account of ‘machine’ which, while acknowledging the physicochemical and organisational differences between man-made machines and biological microscopic devices, nevertheless identifies a common conceptual core that allows us to consider the latter ‘machines’. (shrink)

The issue of damaged relationships and of repairing them is very important, especially in recent years with reports of organizations which damage relationships with various stakeholders. Many studies have investigated how individuals react to damaged relationships after perceiving injustice or receiving offense in organizations. A part of this research has been focused on revenge or other types of negative responses. However, individuals can choose to react in other ways than revenge, willing to repair relationships through reconciliation. Recently, the effectiveness of (...) reconciliation to repair damaged relationship in organizations has been linked to restorative justice. For the purpose of this article we are interested in understanding how restorative justice can be effective in repairing damaged or broken relationships in organizations, as inspired by principles of compassion or mercy. In this sense, we look for a convincing philosophical foundation for restorative justice, proposing Levinas’ ethics as a way to justify it. (shrink)

In this study, we predict the different levels of performance in a Nintendo Entertainment System (NES) Tetris session based on the score and the number of matches played by the players. Using the first 45 seconds of gameplay, a Random Forest Classifier was trained on the five keys used in the game obtaining a ROC_AUC score of 0.80. Further analysis revealed that the number of down keys (forced drop) and the number of left keys (left translation) are the most relevant (...) keys in this task, showing that by merely including the data from these two keys our Random Forest Classifier reached a ROC_AUC score of 0.83.We conclude that the keylogger data during the early phases of a game session can be successfully used to predict performance in longer sessions of Tetris. (shrink)

Serious games are an effective method of reproducing aspects of the complex interplay between environments and stakeholders in business situations. In the game we describe here, The Sustainable Port, players experience what it is like to make decisions in such a complex environment. Their aim in the game is to grow the Port of Rotterdam while keeping economic growth in balance with sustainability goals. In this study, we assessed whether experienced Port of Rotterdam employees (PoR employees) show different psychophysiological patterns, (...) and more specifically EAR-derived features, compared to students. We did this on the assumption that physiological patterns will tell us something about how people who are familiar with the environment of the Port of Rotterdam, more specifically Port of Rotterdam employees, make decisions compared to those lacking such familiarity.Our sample consisted of 28 PoR employees and 65 students, all of whom played The Sustainable Port game and had their faces recorded with a camera. The Eye Aspect Ratio was extracted from these recordings and then from those we extracted EAR-derived features. Our results show that Port of Rotterdam employees perform better than students and that the two groups are characterized by different physiological variations in their EAR-derived features. A logistic regression model used to identify PoR employees and students obtained an F1 score of 0.62, a PR AUC score of 0.64, and a ROC AUC score of 0.70. performing significantly above baseline suggesting the effectiveness of using EAR-derived features for this task. Our interpretation was further confirmed by a pseudo-R2 score used to evaluate the goodness of fit of a logistic regression model on the entire dataset. We found that Port of Rotterdam employees had a lower variation in blink rate per minute (blinks/m) and higher variation in the root mean square difference of successive difference in blinks (RMSSD), the consecutive difference between two continuous blinks. Moreover, this study shows that our methods were robust enough to negate the effects of confounders, such as biological sex and age that affect some other studies that analyze blinks. (shrink)

In this paper, we report on an experiment with The Walking Dead (TWD), which is a narrative-driven adventure game where players have to survive in a post-apocalyptic world filled with zombies. We used OpenFace software to extract action unit (AU) intensities of facial expressions characteristic of decision-making processes and then we implemented a simple convolution neural network (CNN) to see which AUs are predictive of decision-making. Our results provide evidence that the pre-decision variations in action units 17 (chin raiser), 23 (...) (lip tightener), and 25 (parting of lips) are predictive of decision-making processes. Furthermore, when combined, their predictive power increased up to 0.81 accuracy on the test set; we offer speculations about why it is that these particular three AUs were found to be connected to decision-making. Our results also suggest that machine learning methods in combination with video games may be used to accurately and automatically identify complex decision-making processes using AU intensity alone. Finally, our study offers a new method to test specific hypotheses about the relationships between higher-order cognitive processes and behavior, which relies on both narrative video games and easily accessible software, like OpenFace. (shrink)

Il testo vuole testimoniare della piena partecipazione delle scienze sociali alla storia delle scienze, in un quadro di sviluppo che prevede la ricezione in Europa della riforma della filosofia naturale attuata da Francesco Bacone nel XVII secolo e recepita nel principio dell’induzione da Auguste Comte in Francia e da Herbert Spencer in Inghilterra. I temi della fondazione delle scienze sono quindi al centro dell’opera di ricostruzione di eventi cruciali. L’investigazione della natura e del mondo empirico da parte dell’uomo sociale si (...) svolge attraverso i secoli nei modi prescritti dalla filosofia naturale, laddove la tradizione antica e medioevale lasciava irrisolti alcuni problemi di tipo finalistico e vitalistico. Nel Cinquecento e soprattutto nel Seicento assistiamo ad una certa ripresa di tematiche suscitate dall’atomismo e dal meccanicismo in concomitanza del declino della fisica aristotelica. Nel secolo di Cartesio, che rifiutava l’atomismo, la ricerca di una teoria della materia dominò la scena nonché quella del movimento rettilineo uniforme che determinava lo stato di quiete dei corpi, come si nota nei Principia philosophiae del 1644 (pubblicati in francese nel 1647). Il principio che la conoscenza derivasse soltanto dall’interpretazione e dal commento dei testi antichi, sotto una certa forma di principium potestatibus, fu gradualmente sostituito da una filosofia della storia del progresso incarnata nell’ambito della conoscenza scientifica dal metodo sperimentale. La Rivoluzione scientifica culminò con l’applicazione di questa metodologia nella filosofia naturale, nelle scienze della vita (biologia, anatomia, zoologia, botanica), nella medicina e nella chimica, nella fisica (ottica, magnetismo, termologia, elettricità) nonché nella scoperte di William Harvey sulla pressione del sangue, di Evangelista Torricelli sulla pressione dell’atmosfera, Francesco Redi sui corpi viventi e Isaac Newton sulla natura della luce. In particolare, Newton seppe sintetizzare la tradizione dell’empirismo inglese, che va da Ruggero Bacone e Guglielmo di Ockham a John Locke, suo contemporaneo. Il contesto di sviluppo delle idee illuministiche e del positivismo in Francia segnò l’evolversi in Occidente della riflessione più matura sulle scienze e sulle scienze sociali nei vari contesti storico-concreti dove la filosofia naturale poté essere interpretata alla luce di nuove scoperte, le quali dovevano segnare, a loro volta, il momento incisivo di una azione progressiva dell’uomo condotta sulla natura stessa e, in modo tale da fare risaltare, infine, il passaggio al mondo della cultura del progresso. Come è noto, l’idea del progresso sta alla base di tante teorizzazioni della società a partire dal XVIII secolo. Per questo, basterà anche ricordare ciò che Kant pensasse dell’ Illuminismo quando affermava: “L’illuminismo è l’uscita dell’uomo dallo stato di minorità che egli deve imputare a se stesso. Minorità è l’incapacità di servirsi del proprio intelletto senza la guida di un altro. Questa minorità è imputabile a se stesso, se la causa non dipende dalla mancanza di intelligenza ma da mancanza di decisione e del coraggio di far uso del proprio intelletto senza essere guidati da un altro. Sapere aude! Abbi il coraggio di servirti della tua propria intelligenza. È questo il motto dell’illuminismo.” La stessa identificazione data da Auguste Comte nel suo Cours all’uso del termine ‘positivo’ cercava di spiegare come si potesse “considerare tutti i fenomeni come assoggettati a leggi naturali ed invariabili, la scoperta e la riduzione al minor numero possibile delle quali è il fine di tutti i nostri sforzi, considerando inoltre come assolutamente inaccessibile e vuota di senso la ricerca di quelle che si chiamano cause, sia cause prime che quelle finali” (Cours de philosophie positive, I). Al cospetto del nuovo modo di pensare e di operare i temi fondanti dell’intervento umano sulla natura circolavano in concomitanza della diffusione dei saperi scientifici, di quei saperi che si erano manifestati quindi in forma di pratiche illuministiche, cioè di un insieme di ragioni teoriche e pratiche poste in relazione tra loro a beneficio del mondo sociale circostante. Gradualmente anche il tema della rappresentazione dei fenomeni della vita si rapporta allo sviluppo della nuova filosofia naturale, tenendo conto del fatto che le scienze raggiungono uno stadio positivo nonché astratto e concreto (v. Herbert Spencer, The Classification of the Sciences). Ciò sarebbe sufficiente per spiegare il nesso esistente tra le scienze e i fenomeni vitali organici, cioè quel collegamento tra lo sviluppo filosofico e scientifico e il progresso dell’ambiente natura-le e sociale. (shrink)

In this paper, we report on an experiment with The Walking Dead (TWD), which is a narrative-driven adventure game with morally charged decisions set in a post-apocalyptic world filled with zombies. This study aimed to identify physiological markers of moral decisions and non-moral decisions using infrared thermal imaging (ITI). ITI is a non-invasive tool used to capture thermal variations due to blood flow in specific body regions that might be caused by sympathetic activity. Results show that moral decisions seem to (...) elicit a significant decrease in temperature in the chin region 20 seconds after participants are presented with a moral decision. However, given the small sample involved, and the lack of significance in other regions, future studies might be needed to confirm the results obtained in this work. (shrink)

La lettura non è un'invariante antropologica. Essa è invece una pratica che muta secondo i tempi, i luoghi, i contesti, e si dimostra strettamente legata da una parte alle competenze culturali di chi legge, le quali determinano maniere di lettura differenziate, e da un'altra parte alle intenzioni, consuetudini, situazioni entro cui si iscrive l'atto di lettura e che vengono ad esprimersi e a definirsi come modalità, positure fisiche, gesti. Un ruolo fondamentale giocano le forme materiali che lo scritto assume e (...) con le quali il lettore entra in contatto: un testo non esiste di per sé, svincolato da ogni materialità e dunque dal supporto che lo offre alla lettura (o all'ascolto) o dalle circostanze in cui esso viene letto (o ascoltato). Gli autori scrivono testi che diventano oggetti scritti con i quali i lettori instaurano rapporti d'indole varia. I testi possono essere letti diversamente da lettori che non condividono le medesime tecniche o abitudini intellettuali, che non intrattengono una medesima relazione con lo scritto, che non attribuiscono il medesimo significato o il medesimo valore alla lettura, che non iscrivono nelle medesime convenzioni l'atto di leggere. Quando la lettura è ad alta voce, è quest'ultima che fa emergere il senso del testo, e può trasformarsi, nel caso di lettura collettiva, in una performance, nella quale i lettori diventano ascoltatori. Ma la lettura ad alta voce e collettiva ha la funzione non solo di comunicare il contenuto di uno scritto, ma anche quello di cementare solidarietà di gruppo che nella comune cerimonia della performance si riconoscono. Un altro rapporto che può instaurarsi con il libro è quello di una lettura tutta individuale, intima, che può essere tacita o a fior di labbra: una lettura che, se eseguita con la penna in mano, si effettua all'incrocio di lettura e scrittura, giacché può dar luogo ad escerti, parafrasi, trascrizioni, marginalia. O ancora, il rapporto con il libro può risolversi, soprattutto nel caso di lettori “deboli” e privi di strumenti critici, in una maniera di lettura in superficie, che coglie soltanto i significati più semplici e immediati del testo. Tutto questo vale anche per le pratiche di lettura a Bisanzio: ritrovarne alcune tracce è l'intento di questo contributo. (shrink)

This paper investigates whether or not cases of in concreto antinomies (ICAs for short, also called indirect antinomies, accidental antinomies, normative conflicts due to the facts, predicaments, or paranomies) can be predicted. I distinguish two main theoretical positions: “Prodetection” argues that we can predict in concreto antinomies; “unpredictability” argues that we cannot predict them.I exemplify the two positions by relying on a disagreement found in the literature; then, after reviewing that disagreement, I (i) provide arguments for both positions; (ii) highlight (...) the problematic issues for a definition of in concreto antinomy based on conceptual independence; (iii) point out some problems in Martínez Zorrilla’s threefold conception of normative conflicts; and (iv) advocate the need to introduce a case for “practically unpredictable” normative conflicts. (shrink)

I offer a framework for impossibility in the legal domain. I argue for two main points: the use of ‘impossibility’ and ‘impossible’ in the legal domain is often incoherent; in the law we often different concepts of impossibility as well as concepts that differ from impossibility that are nonetheless called ‘impossibility’.

Both physiological and evolutionary criteria of biological individuality are underpinned by the idea that an individual is a functionally integrated whole. However, a precise account of functional integration has not been provided so far, and current notions are not developed in the details, especially in the case of composite systems. To address this issue, this paper focuses on the organisational dimension of two representative associations of prokaryotes: biofilms and the endosymbiosis between prokaryotes. Some critical voices have been raised against the (...) thesis that biofilms are biological individuals. Nevertheless, it has not been investigated which structural and functional obstacles may prevent them from being fully integrated physiological or evolutionary units. By contrast, the endosymbiotic association of different species of prokaryotes has the potential for achieving a different type of physiological integration based on a common boundary and interlocked functions. This type of association had made it possible, under specific conditions, to evolve endosymbionts into fully integrated organelles. This paper therefore has three aims: first, to analyse the organisational conditions and the physiological mechanisms that enable integration in prokaryotic associations; second, to discuss the organisational differences between biofilms and prokaryotic endosymbiosis and the types of integration they achieve; finally, to provide a more precise account of functional integration based on these case studies. (shrink)

Can an event’s blameworthiness distort whether people see it as intentional? In controversial recent studies, people judged a behavior’s negative side effect intentional even though the agent allegedly had no desire for it to occur. Such a judgment contradicts the standard assumption that desire is a necessary condition of intentionality, and it raises concerns about assessments of intentionality in legal settings. Six studies examined whether blameworthy events distort intentionality judgments. Studies 1 through 4 show that, counter to recent claims, intentionality (...) judgments are systematically guided by variations in the agent’s desire, for moral and nonmoral actions alike. Studies 5 and 6 show that a behavior’s negative side effects are rarely seen as intentional once people are allowed to choose from multiple descriptions of the behavior. Specifically, people distinguish between “knowingly” and “intentionally” bringing about a side effect, even for immoral actions. These studies suggest that intentionality judgments are unaffected by a behavior’s blameworthiness. (shrink)

Much of the current research in regenerative medicine concentrates on stem-cell therapy that exploits the regenerative capacities of stem cells when injected into different types of human tissues. Although new therapeutic paths have been opened up by induced pluripotent cells and human mesenchymal cells, the rate of success is still low and mainly due to the difficulties of managing cell proliferation and differentiation, giving rise to non-controlled stem cell differentiation that ultimately leads to cancer. Despite being still far from becoming (...) a reality, these studies highlight the role of physical and biological constraints (e.g., cues and morphogenetic fields) placed by tissue microenvironment on stem cell fate. This asks for a clarification of the coupling of stem cells and microenvironmental factors in regenerative medicine. We argue that extracellular matrix and stem cells have a causal reciprocal and asymmetric relationship in that the 3D organization and composition of the extracellular matrix establish a spatial, temporal, and mechanical control over the fate of stem cells, which enable them to interact and control (as well as be controlled by) the cellular components and soluble factors of microenvironment. Such an account clarifies the notions of stemness and stem cell regeneration consistently with that of microenvironment. (shrink)

An original, theoretical work on cross-linguistic word order from a leading syntactician.